For a regular user, daily caffeine consumption primarily counteracts withdrawal symptoms to return to a functional baseline

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Following Terry Bradshaw's retirement from the NFL, Terry Bradshaw suffered a severe panic attack in Miami that required emergency transport by ambulance

High-dose caffeine administration antagonizes adenosine receptors to transiently restore physical vigor and elevate mood during severe endurance fatigue

Terry Bradshaw underwent three days of brain testing at Yale University, which showed no evidence of dementia or Alzheimer's disease

Former Pittsburgh Steelers center Mike Webster died after experiencing severe cognitive decline, during which Mike Webster lived out of cars and under bridges

Terry Bradshaw took a one-year hiatus from performing in Branson, Missouri, to undergo hip replacement surgery

Katherine May became seriously ill while writing Wintering and could not finish working out her job notice period

Prolonged exposure to cold water during endurance swimming can induce severe hypothermia, rhabdomyolysis, and cellulitis

After a doctor in Miami recommended immediate heart surgery following Terry Bradshaw's panic attack, Bradshaw snuck out of a hospital in the middle of the night

Following his escape from a Miami hospital, Terry Bradshaw flew to a Fort Worth hospital where angiogram tests showed no arterial blockages

Tim Noakes formulated the central governor theory proposing that the brain regulates exercise performance to prevent catastrophic physiological failure

Terry Bradshaw's Merkel cell carcinoma tumor was discovered during an MRI conducted at Yale University to investigate persistent neck spasms

Terry Bradshaw underwent immunotherapy to treat his diagnosis of bladder cancer

The NFL introduced rules to protect players from head injuries in the late 1980s and 1990s following concussions and player deaths linked to chronic traumatic encephalopathy

Katherine May's husband suffered a ruptured appendix and severe sepsis during the writing of Wintering

Terry Bradshaw survived separate diagnoses of bladder cancer and Merkel cell carcinoma

Richard Edgley continued coaching tennis from a wheelchair the day after metastatic melanoma tumors compromised the use of his legs

Prolonged immersion in ocean saltwater draws moisture out of oral tissues, causing the surface layers of the tongue to disintegrate and detach

Ross Edgley applied coconut oil as a topical lipid barrier to protect his tongue and oral mucosa from disintegrating during ocean swims

Ross Edgley developed a severe cellulitis skin infection caused by wetsuit chafing during a 56-hour non-stop swim in Loch Ness

Ross Edgley suffered acute physical collapse and loss of consciousness at the 56-hour mark of his non-stop Loch Ness swim