Alan Chan argues for collecting more data on AI progress as a function of compute and labor costs to estimate the "returns to research effort"

Overview Debates Related claims Topics

Maintaining a decisive strategic advantage achieved via a rapid takeoff is vulnerable to erosion over time through model theft, model distillation, and diffusion

Anthropic conducts early access evaluation testing with external API customers including Cognition

Anthropic conducts internal testing referred to as ant-fooding on candidate model variants prior to cutting versions for external API customers

Biotechnology researchers in Boston have cultured human stem cells into cardiac organoids to generate laboratory-grown heart tissue for direct myocardial injection

Leash Bio utilizes DNA-encoded libraries to screen millions of chemical compounds against thousands of proteins

Since its founding, Leash Bio has screened approximately 1,000 proteins against chemical libraries

Leonardo de Moura developed the Z3 automated theorem prover at Microsoft Research to automatically check software pathways for bugs

Leash Bio produces two pre-measured protein-screening environments per day

Leash Bio established an operational goal to scale production to 20 pre-measured protein-screening environments per day

Research presented at the IEEE Electronic Components and Technology Conference demonstrated hybrid-bonded devices functioning at a 0.45-micrometer pitch

FinFET was demonstrated in a laboratory in 1989 and reached volume production at Intel in 2011

Intel researchers prototype simplified CFET vehicles consisting of one NMOS wire and one PMOS wire to evaluate device stacking

Spencer McIntyre transitioned into exploit research and development after working in cybersecurity consulting

Preclinical mouse studies and molecule discovery typically cost 50 million dollars and take two to three years of drug development

Developing a commercial drug typically takes 15 years and costs approximately 1.5 billion dollars

Clinical trials typically account for more than 1.4 billion dollars and 12 years of drug development costs

In pharmaceutical drug development, preclinical mouse studies typically cost around $50 million over two to three years

In pharmaceutical drug development, clinical trials typically cost over $1.4 billion and span approximately 12 years

Developing a new pharmaceutical drug typically requires approximately 15 years and $1.5 billion

Bringing a single successful drug candidate from early discovery through clinical approval costs between $200 million and over $1 billion