By the third or fourth week of substance abstinence, approximately 80 percent of patients report feeling significantly better

Overview Debates Related claims Topics

Nicholas Guerrel developed the Montreal Model, which combines in-clinic ketamine administration with psychotherapy to treat depression and co-occurring alcohol use disorder

Clinical diagnosis of addiction assesses withdrawal, defined as experiencing a painful physiological response upon discontinuing or reducing substance use

In addicted family systems, a codependent loved one's detachment and relinquishment of control often prompts the addicted individual to enter recovery

Approximately 50 percent of patient referrals to Dr. Anna Lembke's adolescent clinic are for digital media addiction

Clinical diagnosis of addiction assesses tolerance, defined as requiring increased quantities of a drug over time to achieve the same effect

Addiction is clinically defined as the continued compulsive use of a substance or behavior despite harm to oneself or others

Chronic consumption of addictive substances or engagement in addictive behaviors shifts the brain's hedonic set point toward pain, requiring more of the stimulus to achieve neutrality

Glucagon-like peptide-1 receptor agonists reduce alcohol cravings and consumption in certain patients with severe, treatment-refractory alcohol use disorder

Compulsive rumination and obsessive worry can function as an addictive behavior aimed at maintaining an internal sense of control over life uncertainty

A common clinical pattern following an addicted person's recovery is an increase in anger or emergent substance use disorders in their previously codependent partner

Glucagon-like peptide-1 receptor agonists may reduce addictive behaviors by dampening dopamine release in the nucleus accumbens in response to reward cues

Having a biological parent or grandparent with an alcohol use disorder increases an individual's genetic risk for developing an alcohol use disorder

Pia Mellody authored foundational psychological literature examining codependency and emotional enmeshment within addicted family systems

In severe cases of addiction, individuals frequently develop an addiction to exerting personal control over their internal emotional state rather than the specific substance or behavior

In clinical psychiatric settings, individuals termed "rageaholics" exhibit compulsive addictions to the adrenalized physiological arousal produced by anger and conflict

Dr. Anna Lembke serves as the director of the Dual Diagnosis Addiction Clinic at Stanford University School of Medicine

Prescribing addictive medications, including ketamine, benzodiazepines, opioids, or stimulants, to treat legitimate medical conditions does not protect patients from developing addiction

The 12-step recovery model defines a "dry drunk" as an individual who maintains chemical abstinence while continuing to exhibit narcissistic behavioral pathology

In clinical family addiction dynamics, mothers exhibit higher tendencies toward codependent enmeshment while fathers more frequently withdraw and become detached

Clinical diagnosis of addiction assesses the four Cs: out-of-control use, compulsive use, craving, and continued use despite consequences