Microorganisms within the human microbiome assist the human body with physiological regulation and survival

Overview Debates Related claims Topics

Combining histamine H1 receptor blockers and histamine H2 receptor blockers can decrease mast cell activation and localized intestinal inflammation

Inhalation or ingestion of mold toxins can induce mast cell activation and exacerbate chronic digestive inflammation

Soluble fiber acts as a metabolic fuel source for beneficial gut bacteria

Inulin consumption can cause intestinal inflammation comparable to the effects of dietary gluten

Insoluble fiber does not break down during digestion and provides a physical scaffold for gut bacteria

Helminth therapy uses parasitic worms, such as rat tapeworms or pig whipworms, to suppress host intestinal immune inflammation

Fecal microbiota transplantation involves transferring stool from a healthy donor into the gastrointestinal tract of an individual to restore microbial balance

Fecal microbiota transplantation is commonly used in medical settings to treat recurrent Clostridioides difficile infections

Macrophages in the human intestine phagocytose pathogens encountered during digestion

Infants fed infant formula containing corn syrup solids show significantly altered gut microbiome development by six months of age compared to breastfed infants

Rodent studies demonstrate that dietary emulsifier consumption is associated with increased anxiety-like behaviors mediated through microbiome alterations

Unabsorbed sweeteners undergo metabolism by gut microbiota

Increased gut permeability allows intestinal contents to leak into systemic circulation, promoting systemic inflammation

Dietary emulsifiers disrupt the intestinal mucosal barrier, causing increased gut permeability

Gut microbes synthesize short-chain fatty acids including butyrate, acetate, and propionate that deliver anti-inflammatory signals to the human host

Short-chain fatty acids including butyrate, acetate, and propionate repair tight junctions in the gut lining

Viome's laboratory utilizes RNA sequencing assays to measure dynamic gene expression in human and microbial cells rather than static DNA

In a 6,000-person study published in the Microbiome Journal, Viome observed that individual gut microbiomes show statistically significant changes from baseline six months after dietary changes

Trimethylamine produced by gut bacteria travels through the bloodstream and is oxidized in the human liver into trimethylamine N-oxide, a compound linked to heart disease

Viome collects stool, saliva, and finger-prick blood samples from users to analyze human and microbial systems biology