Ketamine-induced uropathy can cause irreversible damage to the bladder wall, including ulceration and fibrosis, which in the most severe cases may require major surgery, bladder removal, or dialysis.

From the articleChildren as young as 13 being referred to UK hospital suffering from ‘ketamine bladder’Also in Teens as young as 13 referred for ketamine-linked bladder problems at UK clinic, 'Peeing a jellyfish': Children's ketamine injuries revealed, Children as young as 13 losing bladder control after getting hooked on ketamine, Children as young as 13 suffering bladder damage caused by ketamine