Approximately 20% of women stop using birth control or change their contraceptive methods within the first six months, frequently due to mood-related side effects such as depression.

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In England, estimated financial costs from adverse childhood experiences were £37.8 billion for mental illness and £22.7 billion for smoking, while in Wales each accounted for £1.8 billion.

The American College of Obstetricians and Gynecologists noted that more than one in three perimenopausal and postmenopausal women report depressive symptoms

The Treatment-Resistant Depression Awareness Day campaign is supported by the National Alliance on Mental Illness, Mental Health America, and the Depression and Bipolar Support Alliance.

Compass Pathways announced the establishment of the first Treatment-Resistant Depression Awareness Day in the U.S. on October 14, 2026.

Treatment-resistant depression is estimated to affect approximately 4 million people in the U.S., with fewer than 5% receiving a treatment indicated for the condition.

A survey commissioned by Compass Pathways revealed that nearly two in three caregivers report treatment-resistant depression impacts family health, with over half experiencing a major toll on their own mental health.

A survey commissioned by Compass Pathways found that nearly 95% of individuals living with treatment-resistant depression describe themselves as functioning but struggling, surviving day-to-day, or barely getting by.

Canada should exclude mental illness as a sole condition for medically assisted dying

Deputy Minister for Women's Health Delyth Jewell stated that Wales' current endometriosis setup is unsustainable and called for a regional or national service model.

Study co-author Shaista Tayabali stated that higher female rates of psychiatric misdiagnosis indicate that historical gender biases remain a challenging aspect of diagnosis.

An international study in eClinicalMedicine found females with autoimmune conditions nearly 75% more likely than males to report a psychosomatic misdiagnosis, with 34% of females affected compared to 22% of males.

A University of Cambridge and University of East Anglia study of over 6,600 autoimmune patients found females almost 50% more likely than males to report psychiatric misdiagnosis, with 43% of females affected versus 33% of males.

Study lead author Dr. Melanie Sloan warned that misdiagnosing physical symptoms as psychological causes long-lasting damage to women's self-esteem and trust in doctors.

Gender bias among clinicians is the primary driver of autoimmune misdiagnosis in women

Dr. Nicholas Leyland of Obstetricians and Gynaecologists of Canada stated that delays in treating severe endometriosis pain reflect gender discrimination within the healthcare system.

A November 2025 House of Commons health committee report found gender bias and societal taboos around menstrual health contribute to an average five-year endometriosis diagnosis delay in Canada.

Outro plans to use its $7 million in capital to expand its network of deprescribing clinicians and develop artificial intelligence clinical decision support tools.

Approximately one in six Americans take an antidepressant medication, and average duration of use has surpassed five years.

Outro's deprescribing platform incorporates personalized hyperbolic tapering plans, compounded medication doses, patient monitoring, and specially-trained clinicians.

Outro plans to expand its tapering model into additional medication classes beyond antidepressants, including benzodiazepines, gabapentinoids, and GLP-1s.