To reduce the risk of eye injury or contamination, patients applying Ryzumvi must avoid touching the vial tip to the eye or any surface

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Patients who wear contact lenses must remove them before applying Ryzumvi eye drops and wait at least 10 minutes before reinserting the lenses

Ryzumvi is not recommended for patients with active ocular inflammation, such as iritis

The MHRA said a credit card-sized patient card is expected to be included in or on antidepressant medicine boxes to reinforce safety messages and provide resource details

The Food and Drug Administration has warned that ibogaine carries severe health risks, including life-threatening irregular heart rhythms and potential brain toxicity.

Multidisciplinary Association for Psychedelic Studies co-executive director Betty Aldworth stated that solving cardiac safety challenges is the central requirement before ibogaine can responsibly reach patients.