Unlike personalized alpha-beta CAR-T therapies, Adicet Bio's prula-cel utilizes gamma-delta T cells, which are designed to secrete fewer inflammatory cytokines and reduce immune-related side effects.

From the articleAdicet Bio Announces Positive Safety and Efficacy Data from Prula-cel (formerly ADI-001) Study in Patients with Systemic Lupus Erythematosus with or without Lupus NephritisAlso in An ‘off-the-shelf’ CAR-T therapy from Adicet shows promise against lupus