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Patients who wear contact lenses must remove them before applying Ryzumvi eye drops and wait at least 10 minutes before reinserting the lenses

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Ryzumvi is not recommended for patients with active ocular inflammation, such as iritis

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To reduce the risk of eye injury or contamination, patients applying Ryzumvi must avoid touching the vial tip to the eye or any surface

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The MHRA said a credit card-sized patient card is expected to be included in or on antidepressant medicine boxes to reinforce safety messages and provide resource details

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The Food and Drug Administration has warned that ibogaine carries severe health risks, including life-threatening irregular heart rhythms and potential brain toxicity.

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Multidisciplinary Association for Psychedelic Studies co-executive director Betty Aldworth stated that solving cardiac safety challenges is the central requirement before ibogaine can responsibly reach patients.