Extensively drug-resistant Shigella outbreak: Drug-resistant Shigella bacteria are rising in the United States, causing severe diarrhea with limited treatment options.

The CDC has issued a public health alert about increasing cases of extensively drug-resistant (XDR) Shigella bacteria in the United States. The proportion of XDR Shigella isolates has risen significantly from 2011-2015 to 2023, with the infection causing severe diarrhea and posing treatment challenges.