Vitalik proposed that Ethereum users configure their partially stateless nodes through an on-chain setting that selects the specific subset of blockchain data to store locally

Quotes that support claims

The system would also allow users to configure what data their node stores, like common smart contracts, tokens, or specific apps, using a simple onchain setting. Users wouldn’t need to store Merkle proofs (the complex cryptographic trees that secure blockchain state), as only raw data suffices.

This means that users could configure their nodes only to save data related to their accounts, the decentralized finance (DeFi) applications and their commonly used tokens like stablecoins and Ether.